Grapefruit products can increase levels of certain heart medications called calcium channel blockers (CCBs). They may recommend a statin that doesn't interact with it or offer other management tips. Talk to your healthcare provider if you take a statin and love grapefruit products. And still, some believe there’s no need to avoid moderate intake of grapefruit products. Others suggest managing this interaction by lowering the statin dose or avoiding large amounts of grapefruit juice. Some experts think avoiding grapefruit juice with statins is best. Statins that aren’t known to interact with grapefruit include rosuvastatin (Crestor), pravastatin, fluvastatin (Lescol XL), and pitavastatin (Livalo).īut it’s not clear how risky the interaction between grapefruit and statins is. The statins most affected by grapefruit are atorvastatin (Lipitor), lovastatin, and simvastatin (Zocor). This can lead to more statin side effects, like muscle pain and possible muscle breakdown ( rhabdomyolysis). But grapefruit and grapefruit juice can increase the levels of certain statin medications. Statins are first-choice options for treating high cholesterol. Some of the most commonly prescribed medications in the U.S., like statin cholesterol medications, are among those that interact with grapefruit.īelow, we’ll detail 11 medications that can interact with grapefruit juice and how you might manage these interactions. This means that grapefruit could affect how well your medication works or could increase your risk of side effects. If you’re a grapefruit lover, you may be disappointed to learn that grapefruit and grapefruit juice can interact with many medications.
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